israa hamdan

work include synthesis five new derivatives for chitosan containing thiazoldinone rings. The synthesized compounds were identified by spectral methods, including FT-IR, 1H-NMR, and 13C-NMR. And study their antibacterial activity with two types of bacteria Staphylococcus arouse and Klebsiella in addition to in-silico study for some important parameters, also predication the LD50 for these compound, also determination of Organ toxicity , Toxicity endpoints, and Rat acute toxicity predicted by GUSAR and Acute Rodent Toxicity Classification of Chemicals by OECD Project