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Protenix

Protenix is an open-source biomolecular structure prediction framework aimed at high-accuracy modeling of proteins and complexes. The repository presents Protenix-v1 as a 368M-parameter model family, with default and application-oriented variants released on 05-02-2026, including support for MSA, RNA MSA, and template features. The project states that Protenix-v1 is the first fully open-source model reported to outperform AlphaFold3 across diverse benchmark sets while matching its training data cutoff, model scale, and inference budget. It is also the foundation for related projects like PXDesign for de novo protein-binder design.
Multimodal Gen 3
Released: February 5, 2026

Overview

Protenix is ByteDance’s open-source biomolecular structure prediction model family for high-accuracy protein and complex structure modeling. It is designed as an accessible foundation for computational biology research, supports protein, RNA MSA, and template features in its latest release, and is positioned as a strong open alternative for structure prediction and downstream biology workflows.

About ByteDance

ByteDance is a multinational technology company known for its content platforms, including TikTok and Douyin.

Industry: Internet
Company Size: 150000
Location: Beijing, CN
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Tools using Protenix

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Last updated: April 2, 2026
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